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KMID : 0369819800100030314
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Jorunal of Korean Pharmaceutical Sciences
1980 Volume.10 No. 3 p.314 ~ p.319
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A Study on the Effects of the Dissociation Constant of Edible Tar Pigment Ⅰ
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김박광/Kim BK
이민화/조영미/김길수/문동철/Lee MH/Cho YM/Kim KS/Moon DC
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Abstract
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The dissociation constant of erythrosine in the mixed solvent systems of water-alcohols and water-acetone at various pH and in concentration media were determined by spectrophotometric method. Methanol, ethanol, and acetone were employed as solvents and studied the changes of pK values of erythrosine according to the kind and change of concentration of organic solvent which is mixed into water solution. The effect of organic solvent on pK is negligible at 40% while in the case of above 40% mixing, it is not negligible.
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